We've got another exciting interconference contest on Wednesday's NBA schedule as the New York Knicks will host the Los Angeles Clippers. New York is 45-26 overall and 24-11 at home, while Los Angeles is 40-31 overall and 15-20 on the road.

Tipoff is set for 7:30 p.m. ET from the Madison Square Garden. The Clippers are 3.5-point favorites in the latest Knicks vs. Clippers odds, according to the SportsLine consensus. The over/under is 217.5 points. Los Angeles is at -151 on the money line (risk $151 to win $100), with New York at +126 (risk $100 to win $126). Before entering any Clippers vs. Knicks picks, you'll want to see the NBA predictions from the model at SportsLine. 

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past six-plus seasons. The model enters Week 23 of the 2024-25 NBA season on a sizzling 153-111 roll on all top-rated NBA picks dating back to last season, returning nearly $4,000. It's also an outstanding 19-10 (65%) on top-rated spread picks this season. Anyone following could have seen HUGE returns!

The model has simulated Knicks vs. Clippers 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread hits on over 50% of simulations!

So who wins Clippers vs. Knicks, and which side of the spread has the better value? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NBA picks!