An Atlantic Division showdown features the New York Knicks (26-15) and the Philadelphia 76ers (15-22) matching up on Wednesday. The Knicks came out with a 124-119 loss in their last game to the Detroit Pistons. As for the 76ers, they have dropped three straight, including a 16-point loss to the Thunder on Tuesday. The Sixers will be without Joel Embiid (foot), while Tyrese Maxey (hand) and Paul George (ankle) are questionable. Karl-Anthony Towns (thumb) is questionable for New York.

Tipoff from Wells Fargo Center in Philadelphia is set for 7 p.m. ET. New York has won four of the last five meetings, including the nly matchup in the 2024-25 NBA season. The Knicks are 7.5-point favorites in the latest Knicks vs. 76ers odds from SportsLine consensus, while the over/under for total points is 217.5, down from opening at 222.5. The Knicks are at -244 on the money line (risk $244 to win $100), with Philadelphia at +199 (risk $100 to win $199).

Before you make any Knicks vs. 76ers picks, you NEED to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past six-plus seasons. The model enters Week 13 of the 2024-25 NBA season on a sizzling 135-97 roll on all top-rated NBA picks dating back to last season, returning well over $3,000. Anyone following could have seen HUGE returns!

The model has simulated Knicks vs. 76ers 10,000 times and the results are in. We can tell you that the model is leaning Over on the point total, and it also says one side of the spread hits in well over 60% of simulations.

Who wins Knicks vs. 76ers, and which side of the spread hits in well over 60% of simulations? ... Join SportsLine right now to find out which side of the spread you should be all over, all from the model on a 135-97 roll on top-rated NBA picks!