The Kentucky Wildcats will open SEC play against the South Carolina Gamecocks on Saturday afternoon. Kentucky cruised to a 31-0 win over Southern Miss last week in a game that was ultimately called off in the third quarter due to weather. South Carolina escaped with a 23-19 win over Old Dominion, using a late turnover to score the game-winning touchdown.  

Kickoff is set for 3:30 p.m. ET on Saturday at Kroger Field. Kentucky is favored by 8.5 points in the latest Kentucky vs. South Carolina odds, while the over/under is 42.5 points, per SportsLine consensus. Before entering any South Carolina vs. Kentucky picks, you'll want to see the college football predictions from the model at SportsLine.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of over $2,000 for $100 players on its top-rated college football picks against the spread. It is also coming off a profitable 13-9 season on top-rated spread picks. Anyone who has followed it has seen strong returns.

The model has simulated Kentucky vs. South Carolina 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 50% of simulations!

So who wins Kentucky vs. South Carolina, and which side of the spread hits well over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks!