The No. 4 Houston Cougars (25-4) and the Kansas Jayhawks (19-10) collide in a Big 12 affair Monday. The Jayhawks had their two-game win streak end Saturday, losing to No. 10 Texas Tech 78-73. Houston has secured eight straight wins, last topping Cincinnati 73-64 Saturday.

Tipoff is scheduled for 9 p.m. ET at Fertitta Center in Houston, Texas. The latest Kansas vs. Houston odds from SportsLine consensus list Cougars as a 9.5-point home favorite, while the over/under for total points scored is 131.5. 

Before entering any Kansas vs. Houston picks, you'll want to see the college basketball predictions from the model at SportsLine.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 18 of the 2024-25 season on a 221-162 roll (+1895) on all top-rated college basketball picks dating back to 2023. Anyone following could have seen HUGE returns!

The model has simulated Kansas vs. Houston 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread hits in 60% of simulations!

So who wins Kansas vs. Houston, and which side of the spread hits in 60% of simulations? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks!