The No. 12 Kansas Jayhawks will host the No. 7 Houston Cougars in a top-15 matchup in Big 12 action on Saturday. Kansas is 14-4 overall, including 5-2 in the Big 12. Houston is 15-3 overall, including 7-0 in the Big 12. The Jayhawks are coming off a 74-61 win over TCU on Wednesday. The Cougars are coming off a 70-36 win over Utah for their 11th straight victory. This is their first meeting this year and Houston and Kansas split their two matchups last season with the home team winning each time. 

Tipoff is set for 6:30 p.m. ET on Saturday from Allen Fieldhouse in Lawrence, Kan. Houston is favored by 1.5 points in the latest Houston vs. Kansas odds, while the over/under is 127.5 points per SportsLine consensus. 

Before entering any Kansas vs. Houston picks, you'll want to see the NCAA Basketball predictions from the model at SportsLine.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 12 of the 2024-25 season on a 198-138 roll (+2692) on all top-rated college basketball picks dating back to 2023. Anyone following could have seen HUGE returns!

The model has simulated Houston vs. Kansas 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting almost 70% of the time.

So who wins Kansas vs. Houston, and which side of the spread hits almost 70% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks.