The No. 1 Kansas Jayhawks will go on the road for a tricky test when they face the Creighton Bluejays in the Big 12-Big East Battle on Wednesday night. Kansas picked up a dramatic win over then-No. 11 Duke in the Vegas Showdown last week before cruising to an 86-51 win over Furman on Saturday. Creighton dropped out of the top 25 following a three-game losing skid, but it responded with an 80-76 win over Notre Dame last weekend.  

Tipoff is set for 8:30 p.m. ET on Wednesday at CHI Health Center Omaha. Kansas is favored by 3.5 points in the latest Kansas vs. Creighton odds, while the over/under is 151.5 points, per SportsLine consensus. Before entering any Creighton vs. Kansas picks, you'll want to see the NCAA Basketball predictions from the model at SportsLine.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 5 of the 2024-25 season on a 170-123 roll (+2061) on all top-rated college basketball picks dating back to 2023. Anyone following has seen HUGE returns!

The model has simulated Kansas vs. Creighton 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in more nearly 70% of simulations!

So who wins Creighton vs. Kansas, and which side of the spread hits nearly 70% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that is on a sizzling 170-123 roll on top-rated CBB picks!