After a breezy 91-65 win over No. 16 seed Holy Cross, Caitlin Clark and the Iowa Hawkeyes will take on No. 8 West Virginia for a spot in the Sweet 16 on Monday. Clark had 27 points, 10 assists, eight rebounds, three steals and a block in Iowa's first-round win and Monday could be something of a grudge match for the NCAA's all-time leading scorer. Mountaineers head coach Mark Kellogg vowed to "send Caitlin Clark packing" while trying to fire up the fan base last week but he downplayed those comments in interviews earlier this week. So will Clark have any extra motivation or will the Mountaineers back up Kellogg's claims?

Tipoff is set for 8 p.m. ET. The Hawkeyes are 14.5-point favorites in the latest Iowa vs. West Virginia odds, while the over/under is 163.5. Before you lock in any West Virginia vs. Iowa picks or predictions, you have to see what women's basketball expert Calvin Wetzel has to say.

Wetzel, HerHoopStats.com lead betting writer, incorporates his mathematical background and strong knowledge of women's hoops to turn the site's prediction model into picks. Now Wetzel has turned his attention to women's college basketball after teaming up with Aaron Barzilai, a Ph.D. from Stanford.

Since the start of the 2021-22 women's college basketball campaign, Wetzel is 1,384-988 (+371.33 units)!

Wetzel knows that Iowa is rolling offensively, having scored at least 90 points in its last 90 games. With Clark leading the way, Lisa Bluder's squad led the nation in scoring this season (92.7 ppg) and ranked second in the nation in field-goal percentage (50.2%). Clark averaged 31.8 points and 10.0 assists per game during Iowa's run to the national championship last season and has registered a double-double in every postseason game she's played so far this season (conference and NCAA). 

Wetzel also has taken into account that West Virginia is one of the better defensive teams in the country and the Mountaineers will certainly be focused on slowing down Clark and the Hawkeyes. Kellogg's squad ground out a 63-53 win over No. 9 Princeton in the first round where the Tigers only shot 33.3% from the floor and turned the ball over 17 times. Ja'Naiya Quinerly had 29 points and seven rebounds and the junior guard is averaging 19.9 points per game this season. 

Now, Wetzel has set his sights on Iowa vs. West Virginia. We can tell you he is leaning Over the total, and he also has a strong play on the side along with a Caitlin Clark prop bet! You absolutely need to see what he says before locking in any women's college basketball picks.

So who wins West Virginia vs. Iowa, and which Caitlin Clark prop bet should be targeting? Join SportsLine right now to find out which picks you should be all over for the NCAA Women's Tournament matchup, all from the expert who is up 371 units since the 2021-22 season!