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Iowa vs. Michigan State odds, line: 2025 college basketball picks, March 6 best bets by proven model

SportsLine's model has locked in its best bets for Thursday's game between the Michigan State Spartans and Iowa Hawkeyes

By@SportsLineUpdated: Mar 06, 2025 9:07PM UTC . 2 min read

The No. 8 Michigan State Spartans can clinch the outright Big Ten regular-season championship when they face the Iowa Hawkeyes on Thursday night. Michigan State clinched a share of the title when second-place Michigan lost to Maryland on Wednesday, handing the Spartans at least a share of the title for the first time since 2019-20. Iowa has lost four of its last five games, falling to Northwestern in a 68-57 final last Friday.  

Tipoff is set for 8 p.m. on Thursday at Carver-Hawkeye Arena. Michigan State is favored by 6.5 points in the latest Iowa vs. Michigan State odds, while the over/under is 154.5 points, per SportsLine consensus. Before entering any Michigan State vs. Iowa picks, you'll want to see the college basketball predictions from the model at SportsLine.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 18 of the 2024-25 season on a 221-162 betting roll (+1895) on all top-rated college basketball picks dating back to 2023. Anyone following at sportsbooks and on betting apps could have seen HUGE returns.

The model has simulated Iowa vs. Michigan State 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 60% of simulations. You can only see the pick at SportsLine.

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