The No. 3 Iowa State Cyclones will try to extend their four-game winning streak when they face the Iowa Hawkeyes in a rivalry tilt on Thursday night. Iowa State took down then-No. 5 Marquette last week before cruising to a blowout win over Jackson State on Sunday. Iowa had its two-game winning streak snapped in an 85-83 loss to Michigan on Saturday. 

Tipoff is set for 7:30 p.m. ET on Thursday at Carver-Hawkeye Arena. Iowa State is favored by 5.5 points in the latest Iowa vs. Iowa State odds, while the over/under is 161.5 points per SportsLine consensus. Before entering any Iowa State vs. Iowa picks, you'll want to see the NCAA Basketball predictions from the model at SportsLine.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 6 of the 2024-25 season on a 174-125 roll (+2196) on all top-rated college basketball picks dating back to 2023. Anyone following has seen HUGE returns!

The model has simulated Iowa State vs. Iowa 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in well over 50% of simulations. 

So who wins Iowa vs. Iowa State? And which side of the spread hits well over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks.