The sixth-seeded Illinois Fighting Illini battle the third-seeded Kentucky Wildcats in a Midwest Region second-round matchup on Sunday. The Fighting Illini (22-12), who have compiled a 46-35 tournament record in 35 appearances, advanced to the Elite Eight last year. The Wildcats (23-11), who are 133-56 in 63 NCAA Tournament appearances, have reached the Elite Eight 34 times, the most all-time.

Tip-off from Fiserv Forum in Milwaukee is set for 5:15 p.m. ET. Illinois is a 1.5-point favorite in the latest Illinois vs. Kentucky odds from SportsLine consensus, while the over/under for total points scored is 167.5. 

Before making any Illinois vs. Kentucky picks, check out the college basketball predictions from the SportsLine Projection Model.

The model simulates every Division 1 college basketball game 10,000 times. It enters the 2025 NCAA Tournament on a 228-166 roll (+2025) on all top-rated college basketball picks dating back to 2023. This model has also produced brackets that have beaten over 91% of CBS Sports entries in four of the last six tournaments and nailed 24 first-round upsets by double-digit seeds! Anyone following could have seen HUGE returns!

The model has simulated Illinois vs. Kentucky 10,000 times and the results are in. We can tell you that the model is leaning Under, and it also says one side of the spread hits in 60% of simulations!

So who wins Illinois vs. Kentucky, and which side of the spread hits in 60% of simulations? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that is 228-166 (+2025) on top-rated college basketball pick and has nailed 24 double-digit upsets!