A berth in the Elite Eight is hanging in the balance when the No. 2 seed Houston Cougars take on the 11th-seeded Syracuse Orange in a Midwest Region Sweet 16 matchup of the NCAA Tournament on Saturday in Indianapolis. Tip-off is at 9:55 p.m. ET at Hinkle Fieldhouse. William Hill Sportsbook lists the Cougars as 6.5-point favorites, while the Over-Under for total points scored is 140.5 in the latest Houston vs. Syracuse odds (see up-to-date lines for every game on our college basketball odds page). 

Before making any Syracuse vs. Houston picks, you NEED to check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past four-plus years, the proprietary computer model has generated an impressive profit of $2,200 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen HUGE returns.

Now, it has set its sights on Houston vs. Syracuse. We can tell you the model is leaning Over the total, and it also says one side of the spread hits over 50 percent of the time! You ABSOLUTELY need to see it before locking in any college basketball picks.

Who wins Houston vs. Syracuse? And which side of the spread hits over 50 percent of the time? ... Join SportsLine right now to find out which side of the Houston vs. Syracuse spread you should be all over Saturday, all from the model on a roll on college basketball picks!