The Cleveland Guardians and Detroit Tigers meet in the second and final game of their series on Tuesday afternoon when they meet at Comerica Park in Detroit. Cleveland defeated Detroit 8-4 on Monday night.

First pitch is scheduled for 1:10 p.m. ET. The Guardians are the -140 money-line favorites (risk $140 to win $100) in the latest Guardians vs. Tigers odds, while the Tigers are +119 underdogs. The over/under for total runs scored is 8.5 in the latest MLB odds via SportsLine consensus. 

Before you make any Guardians vs. Tigers picks or MLB predictions, you need to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every MLB game 10,000 times. It entered Week 19 of the 2024 MLB season 55-48 on all-top rated MLB picks this season. Dating back to last season, it is on a 24-11 roll on top-rated run-line picks (+877). Anybody following has seen STRONG returns!

The model knows Cleveland third baseman Jose Ramirez was 3-for-4 with two homers, one double, three RBI and three runs scored in Monday's win. He has hits in seven of the past nine games, including a 2-for-5 effort with a homer and two RBI in a 5-4 win over the Tigers on July 23. For the season, he is hitting .276 with 23 doubles, one triple, 26 homers and 85 RBI. He has always hit Detroit pitching well. In 128 career games against the Tigers, he is batting .304 with 38 doubles, 10 triples, 32 homers and 118 RBI. 

The model also knows Detroit third baseman Matt Vierling has hits in eight of the past 10 games, including a 2-for-3 effort in Saturday's win over Minnesota. In that game, Vierling stole two bases and scored three times. He was 3-for-5 with two doubles in an 8-2 win over the Guardians on July 22. In 96 games this season, he is batting .256 with 18 doubles, five triples, 13 homers and 42 RBI.

The model has simulated Guardians vs. Tigers 10,000 times and the results are in. We can tell you the model is leaning Over on the run total, and it also says one side of the money line has ALL the value!

Who wins Guardians vs. Tigers, and which side of the money line has ALL the value? ... Join SportsLine right now to find out which side of the money line you should be all over, all from the model on a 24-11 roll on top-rated MLB run-line picks!