The Indianapolis Colts will try to keep their slim playoff hopes alive when they face the New York Giants on Sunday afternoon. Indianapolis has won three of its last five games, including a 38-30 win over Tennessee last week. New York is riding a 10-game losing streak and is in line for the top pick in the upcoming draft. Colts quarterback Joe Flacco is set to start on Sunday with Anthony Richardson (back, foot) sidelined due to injury. 

Kickoff is set for 1 p.m. ET on Sunday at MetLife Stadium. The Colts are favored by 7.5 points in the latest Giants vs. Colts odds, while the over/under is 40.5 points per SportsLine consensus. Before entering any Colts vs. Giants picks, you'll want to see the NFL predictions from the model at SportsLine.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 17 of the 2024 NFL season on a 28-12 hot streak on top-rated NFL picks this year -- a stunning 70% success rate! Longer term, it is on a 208-140 roll on top-rated NFL picks that dates back to the 2017 season and a 62-33 roll on top-rated NFL picks since Week 7 of 2022. 

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone following at sportsbooks and on betting apps has seen strong returns!

The model has simulated Giants vs. Colts 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in nearly 60% of simulations!

So who wins Giants vs. Colts? And which side of the spread hits nearly 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NFL picks.