Americans Taylor Fritz and Frances Tiafoe will play the biggest match of their lives when they meet in the 2024 US Open semifinals on Friday at 7 p.m. ET. It is the first all-American US Open men's singles semifinal since 2005, and one of them will become the first American to play in a men's Grand Slam final since Andy Roddick in the 2009 Wimbledon final. Fritz leads the head-to-head series 6-1, rattling off six consecutive wins since losing the first meeting in 2016. 

Fritz is the -275 favorite (risk $275 to win $100) in the latest Fritz vs. Tiafoe odds, while Tiafoe is the +210 underdog. The over/under for total games is 39.5, with Fritz favored by 3.5 games. Before you make any Tiafoe vs. Fritz picks or 2024 US Open predictions, you need to see what tennis expert Jose Onorato has to say.

Onorato, who holds dual degrees in finance and economics from the University of Miami, does extensive research before placing any tennis bets. He studies current form, players' tendencies on a particular surface, weather conditions and many other relevant factors. That systematic approach has helped Onorato go 168-106-9 (+107.12 units) since 2022. In the 2024 French Open, he correctly picked Iga Swiatek (-160) to win the women's title.

Now, Onorato has taken a close look at this Fritz vs. Tiafoe US Open singles semifinal from all sides. He has identified his winner and a best bet on the spread for Friday's match. You ABSOLUTELY need to see what they are before locking in any 2024 US Open picks of your own!

So where does all the value lie in the Tiafoe vs. Fritz US Open semifinal? And what spread bet is a must-back? ... Join SportsLine right now to see Jose Onorato's predictions and analysis for the 2024 US Open men's singles semifinal, all from the tennis expert who is 168-106-9 since 2022!