The 2025 NCAA Tournament will reach its conclusion on Monday and the national championship will come down to the Florida Gators and Houston Cougars. Both teams were No. 1 seeds when the 2025 March Madness brackets were unveiled and both programs have matching 35-4 records entering Monday's matchup.

Tipoff from the Alamodome in San Antonio is set for 8:50 p.m. ET on CBS. The Gators are 1.5-point favorites in the latest Florida vs. Houston odds from SportsLine consensus, while the over/under for total points scored is 140.5. 

Before making any Houston vs. Florida picks, you'll want to check out the college basketball predictions from red-hot college basketball expert Thomas Casale.

A frequent guest on national radio and TV shows to discuss college sports, Casale has been betting -- and winning -- for more than 30 years. 

He's done well in college basketball, going 341-208 (62.1%) over the last three campaigns. He joined SportsLine in 2024 and promptly went 28-14-1 (67%) in college basketball picks, returning $1,215 to $100 players. He's now 61-38 (+1812) in his last 99 official college basketball plays on SportsLine. Additionally, he is 6-1 (+500) in his last seven picks in Florida games. Anybody who's followed his advice is WAY UP!

For Florida vs. Houston, Casale is leaning Over on the point total, and he also found a critical X-factor that has him jumping on one side of the spread. You ABSOLUTELY NEED to see these picks before locking in any 2025 NCAA Tournament picks of your own.

So who wins Houston vs. Florida, and which side of the spread should you back on Monday in the 2025 NCAA Tournament National Championship Game? Join SportsLine right now to see which side of the spread you need to jump on, all from a red-hot college basketball expert that is on a 61-38 (+1812) run on his CBB picks, and find out. 

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