The Florida State Seminoles will try to bounce back from last week's season-opening upset loss to Georgia Tech when they host the Boston College Eagles on Labor Day at Doak Campbell Stadium in Tallahassee, Fla. Last week in Ireland, the Seminoles were knocked off by the Yellowjackets 24-21 on a 44-yard field goal as time expired. Meanwhile, the Eagles will be playing their first game under former Houston Texans and Penn State head coach Bill O'Brien.

Kickoff is scheduled for 7:30 p.m. ET. The Seminoles are 16.5-point favorites in the latest Florida State vs. Boston College odds via SportsLine consensus, while the over/under for total points scored is 51.5. (See up-to-date odds for every game on our college football odds page.)

Before you make any Boston College vs. Florida State picks, you need to see the college football predictions and betting advice from SportsLine's proven computer model.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of well over $2,000 for $100 players on its top-rated college football picks against the spread. It is also coming off a profitable 13-9 season on top-rated spread picks. Anyone who has followed it has seen strong returns.

The model knows that the Seminoles' pass defense continues to thwart opposing offenses. Last week Florida State allowed just 146 passing yards despite playing an experienced quarterback in Haynes King. Last season, Florida State led the country in opponent completion percentage (48.3), pass breakups (80), passes defended (90) and passes defended per game (6.43).

The model also has taken into account that the Eagles have a running-and-passing threat under center in Thomas Castellanos. A 5-foot-9 junior from Waycross, Ga., Castellanos passed for 2,248 yards and rushed for 1,113 more last season. He became just the fifth player in the ACC since 1996 to produce a 2,000-yard passing, 1,000-yard rushing season.

For Monday, the model has set its sights on Florida State vs. Boston College. We can tell you the model is leaning Over the total, projecting the teams to combine for 59 points. It also says one side of the spread hits in more than 70% of simulations. You absolutely need to see it before locking in any college football picks.

Who wins Boston College vs. Florida State, and which side of the spread hits more than 70% of the time? ... Join SportsLine right now to find out which side of the Florida State vs. Boston College spread you should be all over Monday, all from the model on a roll on college football picks!