The Liberty Flames, who have the nation's longest active regular-season winning streak at 16 games, look to stay perfect on the year when they battle the Florida International Panthers in a key Conference-USA matchup on Tuesday night. The Panthers (2-3, 1-0 CUSA), who are 0-2 on the road this season, are looking to start conference play 2-0 for the first time since 2018. Liberty (4-0, 2-0 CUSA), who won the league championship at 8-0 last season, are 3-0 on their home field in 2024.

Kickoff is set for 7 p.m. ET on CBS Sports Network at Williams Stadium in Lynchburg, Va. Liberty holds a 2-0 series advantage, including a 38-6 victory in Miami last season. The Flames are 16.5-point favorites in the latest FIU vs. Liberty odds via SportsLine consensus, while the over/under for total points scored is set at 55.5. 

Before making any FIU vs. Liberty picks, check out the college football predictions from the SportsLine Projection Model.

The model simulates every FBS college football game 10,000 times. It has generated a profit of well over $2,000 for $100 players on its top-rated college spread football picks since inception, and is 8-4 on top-rated picks over the past two weeks of this season. Anyone who has followed it has seen STRONG returns!

The model knows the Flames are led by redshirt junior quarterback Kaidon Salter. He is coming off a four-TD passing effort in a 35-24 win over East Carolina on Sept. 21. In that game, he completed 19 of 32 passes (59.4%) for 223 yards. For the season, Salter has completed 66 of 103 passes (64.1%) for 949 yards and seven touchdowns with just one interception for a rating of 162.0. He is also Liberty's third-leading rusher, carrying 40 times for 131 yards (3.3 average), including a long of 22 yards.

The model also has taken into account that sophomore quarterback Keyone Jenkins powers the Panthers' offense. He has completed 91 of 145 passes (62.8%) for 1,104 yards and nine touchdowns on the year. He has been intercepted four times, but has a 141.7 rating. He has also rushed for one score. In the win over Louisiana Tech, he completed 17 of 31 attempts (54.8%) for 208 yards and a score. He threw for three touchdowns in a 38-20 loss at FAU on Sept. 14.

The model has simulated FIU vs. Liberty 10,000 times and the results are in. We can tell you the model is leaning Over on the total, and it also says one side of the spread hits over 60% of the time!

Who wins FIU vs. Liberty, and which side of the spread hits over 60% of the time? ... Join SportsLine right now to find out which side of the spread you should be all over, all from the model that is 8-4 over the past two weeks on top-rated CFB picks!