The depth of the Fantasy football rankings was bound to be tested at some point during the season, but with teams now taking bye weeks and Fantasy football injuries mounting, this is by far the hardest stretch of the NFL season. Managers who spent the No. 1 overall pick on Christian McCaffrey were hoping that their superstar running back would finally return to their Week 6 Fantasy football lineups, but San Francisco has already ruled McCaffrey (calf/Achilles) out this week. That's good news if you handcuffed McCaffrey with Jordan Mason, but could create another difficult start-sit decision if you weren't fortunate enough to land Mason on waivers after Week 1.

Before setting your Fantasy football lineups for the 2024 NFL season, you NEED to see the Week 6 Fantasy football rankings from SportsLine's advanced computer model. 

When it comes to ranking players, SportsLine's model beat human experts for the past several seasons, especially when there were big differences in ranking! That could literally be the difference between winning your league or going home empty-handed.

Now the model, which simulates every NFL game 10,000 times, has revealed its latest Week 6 Fantasy football positional rankings.

For Week 5, the model's top three quarterbacks are Lamar Jackson (Ravens), Jalen Hurts (Eagles) and Jordan Love (Packers). Jackson is having his most prolific passing season yet and he's on pace for a 1,000-yard rushing season while Hurts and Love both have intriguing matchups against the Browns and Cardinals, respectively.

The model is also calling for a SHOCKING running back you aren't even thinking about to finish in the top 10 of its Fantasy football rankings! This pick could be the difference between winning BIG and going home with nothing. You ABSOLUTELY need to see who it is before locking in your lineups.

So who should you start and sit in Week 6? And which surprising running back could lead you to victory? ... Join SportsLine now to get Fantasy football rankings for every single position, and see which shocking RB comes out of nowhere to crack the top 10, all from the model that has out-performed experts big-time!