No. 6 seed BYU and No. 11 seed Duquesne are set to square off in the first round of the 2024 NCAA Tournament in the East Region. The Cougars enter March Madness 2024 with a 23-10 overall record, while the Dukes went 24-11 during the regular season. The winner of this game will likely face No. 3 seed Illinois in the second round. 

Tip-off is set for 12:40 p.m. ET at CHI Health Center in Omaha, Neb. The Cougars are 9.5-point favorites in the latest Duquesne vs. BYU odds via SportsLine consensus, while the over/under is 141.5 points (see up-to-date odds for every game this week on our college basketball odds page). Before making any Duquesne vs. BYU picks, you need to check out the college basketball predictions from the SportsLine Projection Model.

The model simulates every Division I college basketball game 10,000 times. It enters the 2024 NCAA Tournament on a 148-106 roll on all top-rated college basketball picks dating back to last season, returning more than $1,700 for $100 players. It also has a strong 29-19 (+810) record on top-rated spread picks this season. Anyone following has seen HUGE returns!

The model has factored in the Cougars have four players who are averaging 10 or more points per game, led by senior guard Jaxson Robinson, who primarily comes off the bench. In 32 games, including six starts, he is averaging 13.8 points, 2.5 rebounds and 1.3 assists in 26.3 minutes. He is in his second season with BYU, after playing his freshman season at Texas A&M and his sophomore year at Arkansas. He is coming off an 18-point and five-rebound effort in the quarterfinal loss to Texas Tech on Thursday.

The model has also considered the Dukes have been led by senior guard Dae Dae Grant. The fifth-year player in his second season at Duquesne, has played in 32 games, including 30 starts, and is averaging 16.7 points, 3.4 rebounds, 2.5 assists and one steal in 32.8 minutes. He has reached double-digit scoring in each of the last four games, including a 27-point performance in a 70-60 win over St. Bonaventure in the Atlantic 10 semifinals. In the league's title game, he scored 10 points and added four steals and two assists. He is connecting on 93.9% of his free throws.

Now, the model has set its sights on Duquesne vs. BYU. We can tell you the model is leaning Over on the point total, and it also says one side of the spread hits in well over 50% of computer simulation! You ABSOLUTELY need to see it before locking in any college basketball picks.

Who wins Duquesne vs. BYU, and which side of the spread hits well over 50% of the time? ... Join SportsLine right now to find out which side of the spread you should be all over, all from that's on a 29-19 roll on top-rated college basketball spread picks!