The No. 1 seed Duke Blue Devils are expected to be without ACC Player of the Year Cooper Flagg when they face the No. 5 seed North Carolina Tar Heels on Friday night. Flagg suffered a sprained left ankle in a quarterfinal win over Georgia Tech on Thursday after landing on an opponent's foot in the first half. North Carolina could possibly secure an at-large bid to the NCAA Tournament with an upset win on Friday after notching wins over No. 12 seed Notre Dame and No. 4 seed Wake Forest already this week. 

Tipoff is set for 7 p.m. on Friday at the Spectrum Center in Charlotte. Duke is favored by 7.5 points in the latest Duke vs. North Carolina odds, while the over/under is 154.5 points, per SportsLine consensus. Before entering any North Carolina vs. Duke picks, you'll want to see the college basketball predictions from the model at SportsLine.

The model simulates every Division 1 college basketball game 10,000 times. It enters conference championship week on a 225-165 roll (+1873) on all top-rated college basketball picks dating back to 2023. Anyone following could have seen HUGE returns!

The model has simulated Duke vs. North Carolina 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in well over 60% of simulations. You can only see the pick at SportsLine.

So who wins Duke vs. North Carolina? And which side of the spread hits well over 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks.