The No. 1 seed Duke Blue Devils will try to get another game closer to a national championship when they face the No. 4 seed Arizona Wildcats in the NCAA Tournament Sweet 16 Thursday night. Duke cruised to a pair of blowout wins over No. 16 seed Mount St. Mary's and No. 9 seed Baylor last weekend, while Arizona easily beat No. 13 seed Akron before sneaking past No. 5 seed Oregon. Duke notched a 69-55 road win at Arizona when these teams met in November. 

Tipoff from the Prudential Center in Newark is set for 9:39 p.m. ET. The Blue Devils are 9.5-point favorites in the latest Duke vs. Arizona odds from SportsLine consensus, while the over/under for total points scored is 154.5, up one from the opening line. The Blue Devils are -190 favorites in the race to 10 points. Before making any Arizona vs. Duke picks, you won't want to miss the college basketball predictions from red-hot college basketball expert Bruce Marshall.

For years, the Vegas-based Marshall was synonymous with The Gold Sheet, the famed sports betting newsletter. With a background in play-by-play work and sports information while in college, Marshall joined TGS in 1981 when hired by the legendary Mort Olshan and served as executive editor for many years. Marshall now supplies his unique and colorful brand of football and basketball analysis to SportsLine members.

Marshall enters the Sweet 16 of the 2025 NCAA Tournament on a 93-62-1 roll (+2419) over his last 156 college basketball picks. Anybody who's followed his picks could be WAY UP!

For Duke vs. Arizona, Marshall is leaning Over on the total, and he also found a critical x-factor that has him jumping on one side of the spread. You ABSOLUTELY NEED to see these picks before locking in any 2025 NCAA Tournament picks of your own.

So who wins Duke vs. Arizona, and which side of the spread should you be hammering? Join SportsLine right now to see which side of the spread you need to jump on, all from a red-hot college basketball expert that is on a 93-62-1 run (+2419) on his hoops picks!