The No. 3 seed Texas Tech Red Raiders and No. 11 seed Drake Bulldogs square off in the second round of the 2025 NCAA Tournament on Saturday. The Red Raiders knocked off the UNC Wilmington 82-72 in a first-round bout on Thursday. However, the Bulldogs upset the No. 6 seed Missouri Tigers 67-57. 

Tipoff from the Intrust Bank Arena in Wichita, Kansas, is set for 6:10 p.m. ET. Texas Tech is a 6.5-point favorite in the latest Drake vs. Texas Tech odds from SportsLine consensus, while the over/under for total points scored is 126.

Before making any Drake vs. Texas Tech picks, check out the college basketball predictions from the SportsLine Projection Model.

The model simulates every Division 1 college basketball game 10,000 times. It enters the 2025 NCAA Tournament on a 228-166 roll (+2025) on all top-rated college basketball picks dating back to 2023. This model has also produced brackets that have beaten over 91% of CBS Sports entries in four of the last six tournaments and nailed 24 first-round upsets by double-digit seeds! Anyone following could have seen HUGE returns!

The model has simulated Drake vs. Texas Tech 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread cashes in over 50% of simulations!

So who wins Drake vs. Texas Tech, and which side of the spread cashes in over 50% of simulations? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that is 228-166 (+2025) on top-rated college basketball pick and has nailed 24 double-digit upsets!