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Diamondbacks vs. Marlins line, odds, start time, spread pick, best bets for April 17 matchup from proven model

SportsLine's projection model, which is on a profitable 8-3 run, has locked in its MLB picks for Arizona Diamondbacks vs. Miami Marlins on Thursday as Arizona goes for the series sweep

ByUpdated: Apr 17, 2025 3:36PM UTC . 3 min read

The Arizona Diamondbacks look for the series sweep when they battle the Miami Marlins in a National League matchup on Thursday afternoon. The Diamondbacks (11-7), who have won four in a row, are 5-3 on the road this season. The Marlins (8-9), who have lost five of eight, are 6-6 on their home field.

First pitch from loanDepot Park in Miami is set for 12:10 p.m. ET. Arizona is a -155 favorite on the money line (risk $155 to win $100) in the latest Diamondbacks vs. Marlins odds from SportsLine consensus, while the total number of runs Vegas thinks will be scored, or the over/under, is 8.5. Arizona is -190 to score the first run of the game. 

Before making any Diamondbacks vs. Marlins picks or MLB predictions, you need to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every MLB game 10,000 times. It enters Week 4 of the 2025 MLB season on an 8-3 run on top-rated money-line picks (+340). Anybody following could have seen strong returns!

The model knows left-hander Eduardo Rodriguez (0-2, 4.86 ERA) is expected to take the mound for Arizona. In a 7-0 loss to the Milwaukee Brewers on Friday, he pitched 6.1 innings, allowing six hits, three runs—two earned—with two walks and three strikeouts. In a 4-3 loss at Washington on April 5, he pitched five innings, allowing four earned runs and one walk, while striking out 12. He is in his second season with the Diamondbacks. In 10 games in 2024, all starts, he was 3-4 with 19 walks and 47 strikeouts.  

The model also knows Miami will send right-hander Edward Cabrera (0-0, 3.18 ERA) to the mound. He received a no-decision in a 7-4 loss to Washington on Friday. In 5.2 innings pitched, he allowed four hits, two runs—all earned—with three walks and five strikeouts. In two career starts against Arizona, he is 0-1. He was 4-8 a year ago with a 4.95 ERA.

The model has simulated Diamondbacks vs. Marlins 10,000 times and the results are in. We can tell you the model is leaning Over on the run total, and it also says one side of the money line has ALL the value!

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Daniel Kohn

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