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2025 NCAA Tournament Final Four score predictions: College basketball picks from red-hot hoops experts

The team of experts at SportsLine reveal their 2025 March Madness Final Four score predictions for both games in San Antonio on Saturday

The 2025 NCAA Tournament has reached the Final Four and the action begins on Saturday with the two national semifinals on CBS. For the second time in the history of March Madness, all four No. 1 seeds advanced to the Final Four, and now we'll see Auburn, Houston, Duke and Florida battle it out for the title. Auburn vs. Florida (-2.5, 159.5) begins at 6:09 p.m. ET, while Duke (-5.5, 136.5) vs. Houston will follow at 8:49 p.m. ET. Duke is the -115 favorite to win it all. 

Auburn's Johni Broome, who recorded 25 points and 14 rebounds in the Elite Eight, returned to practice for Auburn on Thursday with an arm injury.

Before making any college basketball picks or making any 2025 March Madness Final Four score predictions, you NEED to see what the college basketball experts at SportsLine have to say. 

Thomas Casale, Jason La Canfora, Larry Hartstein, Bruce Marshall and Chip Patterson have all been making college basketball picks for SportsLine throughout the season and they all enter the Final Four on dominant winning streaks. Casale is 61-37 entering the final weekend of the college basketball season while La Canfora is 74-51-1, Hartstein is 61-45, Marshall is 99-72-1 and Patterson is on a 7-2-1 heater. Anybody who's followed their advice during those stretches is WAY UP!

We can tell you that La Canfora is predicting that Florida takes down top overall seed Auburn 83-78 in the first national semifinal! "Two powerful offensive teams, but this could be a little slower due to nerves, new surroundings and all that jazz. Florida has been a little more consistent than the Tigers. The Gators dropped 90 on Auburn at Auburn, which is hard for me to forget, and probably hard for the Tigers to forget," La Canfora told SportsLine.

One of SportsLine's top college basketball experts is all-in on a team that's a "covering machine"! You ABSOLUTELY NEED to see which team it is before making any college basketball picks of your own.

Who should you back in the 2025 NCAA Tournament Final Four and which "covering machine" is a MUST-BACK? ... Join SportsLine now to find out, all from a team of red-hot college basketball handicappers who have been locked in on college basketball all season!

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SportsLine Staff
SportsLine Staff

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