We've got another exciting Big 12 matchup on Tuesday CBB schedule as the No. 17 Kansas Jayhawks are set to host the Colorado Buffaloes at Allen Fieldhouse. Kansas is 16-7 overall and 11-2 at home, while Colorado is 9-14 overall and 0-6 on the road. The Buffs are winless in Big 12 conference play and looking to snap a 12-game losing streak. CU lost to Houston 69-59 in its last outing. Kansas is looking to bounce back from an 81-73 loss to Kansas State on Feb. 8. 

Tipoff in Lawrence, Kansas is at 9 p.m. ET. Kansas is favored by 16.5 points in the latest Kansas vs. Colorado odds, and the over/under is 141.5 points. Before entering any Kansas vs. Colorado picks, you'll want to see the college basketball predictions and betting advice from the proven computer simulation model at SportsLine.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 15 of the 2024-25 season on a 211-154 roll (+2024) on all top-rated college basketball picks dating back to 2023. Anyone following could have seen HUGE returns!

The model has simulated Colorado vs. Kansas 10,000 times and the results are in. We can tell you that the model is leaning Over on the point total, and it's also generated a point-spread pick that hits well over 50% of the time!

So who wins Kansas vs. Colorado, and which side of the spread hits well over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks!