The No. 8 Michigan Wolverines host the Colorado State Rams in the season opener for both teams at noon ET on Saturday. Michigan is favored by 31 points at Caesars Sportsbook, while the over/under is set at 61.5 (see up-to-date odds for every game this week on our college football odds page). 

Before making any Colorado State vs. Michigan picks, you NEED to check out the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,600 for $100 players on its top-rated college football picks against the spread. It enters Week 1 of the 2022 college football season on a 45-32 run on all top-rated college football spread and money-line picks that dates back to 2021. Anyone who has followed it has seen huge returns.

The model knows Colorado State overhauled its offense with an infusion from Nevada. The Rams have a new head coach in Jay Norvell, who brought with him key pieces at quarterback and wide receiver. Colorado State also returns its top two wide receivers from 2021, and the Rams produced 39 sacks on defense last season, leading the Mountain West. The model also knows that Michigan lost considerable talent from last year's College Football Playoff team, but the Wolverines return a two-headed monster at quarterback with an elite rushing option in Blake Corum. Michigan led the Big Ten in rushing a year ago, and the Wolverines project to have one of the best offensive lines in college football this season.

Now, it has set its sights on Colorado State vs. Michigan. We can tell you the model is leaning Under the total, and it also says one side of the spread hits in 70% of simulations! You ABSOLUTELY need to see it before locking in any college football picks.

Who wins Colorado State vs. Michigan? And which side of the spread hits in 70% of simulations? ... Join SportsLine right now to find out which side of the Colorado State vs. Michigan spread you should be all over Saturday, all from the model on a roll on college football picks!