The Week 5 college football schedule will feature multiple ranked teams looking to bounce back from losses, including No. 11 Notre Dame. The Fighting Irish came up just short against Ohio State last week, but they are still alive for a College Football Playoff berth heading into their game at No. 17 Duke (+5.5). Meanwhile, No. 20 Ole Miss is looking to rebound from its loss to Alabama, hosting No. 13 LSU (-2.5) on Saturday night. The 3:30 p.m. ET SEC on CBS matchup features Auburn hosting top-ranked Georgia, with the Bulldogs favored by 14.5 points in the latest Week 5 college football odds. And after opening at -24.5, USC is -21.5 as it takes on Deion Sanders and Colorado at noon ET.

Before making any college football picks for those games or others in Week 5, be sure to see what the SportsLine Projection Model has to say. 

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, it has generated a stunning profit of nearly $2,500 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen HUGE returns.  

Now, it has studied the latest college football odds (see the latest college football lines for each matchup this week on our college football odds page), simulated every single play for every Week 5 game, and the results are in. 

One of the college picks the model is high on during Week 5: Georgia (-14.5) easily covers the spread at Auburn in a 3:30 p.m. ET SEC on CBS kickoff at Jordan-Hare Stadium. The Bulldogs improved to 4-0 with a 49-21 win against AUB last week, while Auburn's offense sputtered in a 27-10 loss at Texas A&M. Georgia has won and covered the spread in the last six meetings between these teams, and the Bulldogs are covering in well over 60% of the model's simulations. 

Another prediction: Michigan State (+10.5) plays a competitive road game at Iowa on Saturday at 7:30 p.m. ET. The Spartans have been held to single digits in their last two games, but they are facing a much weaker offense this week. Iowa is coming off a shutout loss to Penn State, and it has lost four of its last six games against Michigan State. That is one reason why the Spartans are covering the spread 70% of the time. Despite the total being listed at just 36.5, the model is going Under on that, saying that cashes well over 50% of the time.

The model has also made the call on who wins and covers in every other FBS matchup, and it's calling for multiple underdogs to win outright!

So which college football teams should you back in Week 5, and which underdogs win outright? ... Join SportsLine now to see who wins and covers every single game, all from the model that has returned nearly $2,500 in profit on top-rated ATS picks since its inception!