While there are not any top-25 teams going head-to-head in the Week 3 college football schedule, there are plenty of games that could impact the College Football Playoff picture. No. 11 Tennessee travels to Florida seeking its first win in Gainesville since 2003, with the Volunteers favored by seven points in the Week 3 college football odds from SportsLine consensus. No. 10 Alabama will try to bounce back from its loss to Texas when it travels to South Florida as a heavy road favorite, while Michigan State hosts No. 8 Washington. 

Before making any college football picks for those games or others in Week 3, be sure to see what the SportsLine Projection Model has to say. 

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, it has generated a stunning profit of almost $2,500 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen HUGE returns.  

Now, it has studied the latest college football odds (see the latest college football lines for each matchup this week on our college football odds page), simulated every single play for every Week 3 game, and the results are in. 

One of the college picks the model is high on during Week 3: No. 11 Tennessee (-5.5) wins by double digits at Florida in a 7 p.m. ET kickoff at Ben Hill Griffin Stadium. Tennessee has not won in Gainesville since 2003, but it beat the Gators last year and is off to a 2-0 start this season. Florida opened the year with a double-digit loss at Utah, and the model has the Vols covering the spread in 60% of simulations. 

Another prediction: Purdue (+2.5) beats Syracuse outright on Saturday at 7:30 p.m. ET. The Boilermakers bounced back from a season-opening loss to Fresno State with a 24-17 win at Virginia Tech last week. They were 1-point underdogs against the Hokies, but they controlled nearly 40 minutes of the possession in the win. The model has Purdue springing another upset on Saturday, as the Boilermakers are covering the spread 70% of the time. 

The model has also made the call on who wins and covers in every other FBS matchup, and it's calling for multiple other underdogs to win outright!

So which college football teams should you back in Week 3, and which underdogs win outright? ... Join SportsLine now to see who wins and covers every single game, all from the model that has returned almost $2,500 in profit on top-rated ATS picks since its inception!