The No. 5 Indiana Hoosiers will try to prove themselves to the country when they face the No. 2 Ohio State Buckeyes on Saturday afternoon (noon ET) in the biggest game on the Week 13 college football schedule. Indiana has won its first 10 games this season, but it has not faced a ranked opponent. The Hoosiers are 10-point road underdogs in the Week 13 college football odds from SportsLine consensus. 

The other ranked vs. ranked matchups on Saturday pit No. 6 Notre Dame (-14) vs. No. 19 Army in a 7 p.m. ET kickoff and No. 21 Arizona State vs. No. 14 BYU (+3.5) at 3:30 p.m. ET. Army joins Indiana and Oregon as the only undefeated teams in college football, but the Black Knights are also playing their first ranked team of the season. Elsewhere, No. 3 Texas is a 20.5-point favorite at home against Kentucky (3:30 p.m. ET). 

Before making any college football picks for those games or others in Week 13, be sure to see what the SportsLine Projection Model has to say. 

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of well over $2,000 for $100 players on its top-rated college spread football picks, and it is a strong 21-15 on all top-rated picks over the past eight weeks of this season. Anyone following has seen STRONG returns

Now, it has studied the latest college football odds (see the latest college football lines for each matchup this week on our college football odds page), simulated every single play for every Week 13 game, and the results are in. 

One of the college picks the model is high on during Week 13: No. 16 Colorado (-2.5) covers the spread on the road against Kansas in a 3:30 p.m. ET matchup on Saturday, with the Buffaloes covering in nearly 60% of simulations.

Another prediction: No. 15 Texas A&M (-2.5) keeps its College Football Playoff hopes alive with a win at Auburn in a 7:30 p.m. ET kickoff on Saturday. The model has the Aggies covering well over 60% of the time. 

The model has also made the call on who wins and covers in every other FBS matchup, and it's calling for a whopping 12 underdogs to win outright!

So which college football teams should you back in Week 13, and which underdogs win outright? ... Join SportsLine now to see who wins and covers every single game, all from the model that has returned well over $2,000 in profit on top-rated ATS picks since its inception! ... You've unlocked our best deal! Get your first month of SportsLine for ONLY $1 with the promo code "LEAGUE"! Join here!