The No. 8 USC Trojans and the No. 12 UCLA Bruins will meet for a critical Pac-12 matchup when they square off on Saturday night during the Week 12 college football schedule. USC is on a three-game winning streak and is sitting atop the conference standings following a 55-17 win over Colorado in Week 11. The Trojans are 2.5-point favorites in the latest Week 12 college football odds at Caesars Sportsbook, while the over/under is 76. There is another important Pac-12 game on Saturday night as well, with No. 6 Oregon playing host to No. 13 Utah (-2). 

Before making any college football picks for those games or others in Week 12, be sure to see what the SportsLine Projection Model has to say.

The SportsLineProjection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen HUGE returns.  

Now, it has studied the latest college football odds from Caesars (see the latest college football lines for each matchup this week on our college football odds page), simulated every single play for Week 12 of FBS college football, and the results are in. 

One of the college picks the model is high on in Week 12: Cincinnati (-17) cruises to an easy win at Temple on Saturday afternoon. The Bearcats have won eight of their last nine games, including five double-digit victories. Temple has been trending in the opposite direction, losing five of its last six games. The Owls are coming off a tough road loss at Houston, which is one reason why the model has Cincinnati covering the spread almost 70% of the time. 

Another prediction: No. 24 Oklahoma State easily stays within the 7.5-point spread in its Bedlam Series rivalry matchup at Oklahoma on Saturday night. The Cowboys bounced back from their two-game losing streak with a 20-14 win against Iowa State last week, pulling off the outright upset as 2.5-point underdogs. Oklahoma is coming off consecutive losses to Baylor and West Virginia, and it has now lost five games this season. The Sooners are not deserving of being heavy favorites in this game, which is why Oklahoma State is covering in almost 70% of simulations. 

The model has also made the call on who wins and covers in every other FBS matchup, and it's calling for several top-20 teams to go down HARD! 

So which college football teams should you back this week? And which top-20 teams go down HARD? ... Join SportsLine now to see who wins and covers every single game, all from the model that has returned almost $3,000 in profit on top-rated ATS picks over the past six-plus seasons!