The reigning Super Bowl champion Kansas City Chiefs attempt to extend a pair of winning streaks when they visit the AFC West-rival Los Angeles Chargers in Week 4 of the 2024 NFL season on Sunday. Kansas City (3-0) is seeking its ninth consecutive overall victory, including the playoffs, dating back to last campaign and its 11th in a row against the Chargers on the road. The Chiefs haven't suffered a road loss in the series since Week 17 of the 2013 season, when they fell 27-24 in overtime when the Chargers called San Diego home.

Kansas City began the year with home wins against the Baltimore Ravens and Cincinnati Bengals before defeating the Falcons 22-17 in Atlanta last weekend. Los Angeles (2-1) is coming off a 20-10 road setback against the Pittsburgh Steelers after getting off to a 2-0 start with triumphs over the Las Vegas Raiders and Carolina Panthers. Quarterback Justin Herbert exited the loss with an ankle injury and is said to be progressing, but his status for the matchup with the Chiefs is up in the air.

Overall, Kansas City has won five straight meetings with Los Angeles and 17 of the last 20 to improve to 69-57-1 in the regular-season series. Despite their recent road dominance, eight of the Chiefs' wins during their 10-game streak have been by 10 points or fewer, and each of the last five were one-score decisions - including two in overtime.

Patrick Mahomes will be making the 100th start of his NFL career on Sunday. Entering the contest, the two-time NFL MVP already has the most wins (77), passing yards (29,083) and touchdown tosses (224) through 100 starts in league history.

Despite resting most of their starters, the Chiefs posted a 13-12 victory at Los Angeles in Week 17 last season. When the teams met at SoFi Stadium in 2022, Mahomes threw for 329 yards and three TDs - all to tight end Travis Kelce, who amassed 115 receiving yards - as Kansas City edged the Chargers 30-27. For their Week 4 showdown on Sunday, the Chiefs are 7-point favorites in the latest odds via SportsLine consensus, while the over/under for total points is 39.5. 

We'll take you through every aspect of the Chiefs-Chargers game that you need to know before you lock in your bets, including SportsLine expert picks, props, trends, injury information and everything else that will help you know which plays are worth making for the contest.

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