The Boston Celtics will host the Los Angeles Lakers in a NBA rivalry game on Saturday at the TD Garden. Los Angeles is 40-21 overall and 15-14 on the road, while Boston is 45-18 overall and 21-11 at home. The Lakers have won eight straight games, including a 113-109 win over the New York Knicks in their last outing. The Celtics are riding a three-game winning streak, and are looking to build off their 123-105 win over the Philadelphia 76ers on Thursday. 

Tipoff in Boston is at 8:30 p.m. ET. The Celtics are favored by 7 points in the latest Lakers vs. Celtics odds via SportsLine consensus, and the over/under is 226.5 points.

Before entering any Lakers vs. Celtics picks, you'll want to see the NBA predictions and betting advice from the proven computer simulation model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past six-plus seasons. The model enters Week 20 of the 2024-25 NBA season on a sizzling 147-107 roll on all top-rated NBA picks dating back to last season, returning nearly $4,000. It's also an outstanding 18-10 (64%) on top-rated spread picks this season. Anyone following at sportsbooks and on betting apps could have seen huge returns.

The model has simulated Lakers vs. Celtics 10,000 times and the results are in. We can tell you that the model is leaning Over on the point total, and it's also generated a point-spread pick that is hitting in well over 60% of simualations!

So who wins Celtics vs. Lakers, and which side of the spread hits well over 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NBA picks!