The two top teams in the Atlantic Division square off when the Boston Celtics battle the New York Knicks in a key Eastern Conference matchup on Tuesday. The Celtics (58-20), who are the second seed in the East, are 32-7 on the road this season. The Knicks (50-28), the third seed in the East, are 27-12 on their home floor in 2024-25. Jayson Tatum (ankle), Jaylen Brown (knee) and Kristaps Porzingis (illness) are all questionable for Boston.

Tip-off from Madison Square Garden in New York is set for 7:30 p.m. ET. The Knicks are 1-point favorites in the latest Celtics vs. Knicks odds from SportsLine consensus, while the over/under for total points scored is 222. New York is at -115 on the money line (risk $115 to win $100), while Boston is at -104 (risk $104 to win $100).

Before making any Celtics vs. Knicks picks, check out the NBA predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past six-plus seasons. The model enters the final week of the 2024-25 NBA regular season on a sizzling 155-115 roll on all top-rated NBA picks dating back to last season, returning nearly $4,000. It's also an outstanding 21-10 (68%) on top-rated spread picks this season. Anyone following could have seen HUGE returns!

The model has simulated Celtics vs. Knicks 10,000 times and the results are in. We can tell you that the model is leaning Over on the point total, and it also says one side of the spread hits in over 60% of simulations!

Who wins Celtics vs. Knicks, and which side of the spread hits over 60% of the time? ... Join SportsLine right now to find out which side of the spread you should be all over, all from the model on a 155-115 roll on top-rated NBA picks!