The Boston Celtics (49-30) go on the road to play the Chicago Bulls (45-34) in an Eastern Conference contest on Wednesday night at 8 p.m. ET. Boston is favored by seven points in the latest Celtics vs. Bulls odds from Caesars Sportsbook, while the Over-Under is set at 224 (see up-to-date odds for every game this week on our NBA odds page). 

Before making any Celtics vs. Bulls picks, you NEED to check out the NBA predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past three-plus seasons. The model enters Week 25 of the 2021-22 NBA season on a stunning 84-54 roll on all top-rated NBA picks, returning over $2,400. Anyone following it has seen HUGE returns!

The model knows Boston forward Jayson Tatum is one of the most gifted scorers in the league. Tatum has fantastic footwork and can score from anywhere on the floor. The three-time All-Star is eighth in the NBA in points (27) with eight rebounds, and 4.4 assists per game. Tatum is savvy on the offensive end and knows how to draw contact from defenders. He shoots 85 percent from the free-throw line. On April 1, Tatum finished with 31 points, six rebounds, and six assists. 

The model also knows Bulls forward DeMar DeRozan is an elite scorer and a mid-range assassin. DeRozan has a great first step, constantly driving to the basket. The USC product is sixth in scoring (28), along with 5.3 rebounds, and five assists per game. On Mar. 31, the five-time All-Star dropped 50 points, five rebounds, and six assists. 

Now, it has set its sights on Celtics vs. Bulls. We can tell you the model is leaning Over the total, and it also says one side of the spread hits in almost 60 percent of simulations! You ABSOLUTELY need to see it before locking in any NBA picks.

Who wins Celtics vs. Bulls? And which side of the spread hits in almost 60 percent of simulations? ... Join SportsLine right now to find out which side of Celtics vs. Bulls spread you should be all over Wednesday, all from the model on a roll on NBA picks!