The Cleveland Cavaliers will face off against the Los Angeles Lakers at 7 p.m. ET on Wednesday at Rocket Mortgage FieldHouse. Cleveland is 4-0 overall and 1-0 at home, while Los Angeles is 3-1 overall and 0-1 on the road. The Cavaliers are favored by 4.5 points in the latest Cavaliers vs. Lakers odds, and the over/under is 225.5 points.

Before entering any Lakers vs. Cavaliers picks, you'll want to see the NBA predictions from the model at SportsLine.

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The model has simulated Cavaliers vs. Lakers 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that hits in over 60% of simulations. You can only see the pick at SportsLine.

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