The top two teams in the Eastern Conference square off when the Cleveland Cavaliers battle the Boston Celtics on Friday night. Cleveland is coming off a 122-82 win at Orlando on Tuesday, while Boston dropped a 117-97 decision at Detroit on Wednesday. The Cavaliers (48-10), first in the Eastern Conference and the Central Division, have won eight in a row. The Celtics (42-17), second in the East and first in the Atlantic Division, have won eight of their last 10 games. Jaylen Brown (thigh) is questionable for Boston.

Tip-off from TD Garden in Boston is set for 7:30 p.m. ET. The Celtics are 1.5-point favorites in the latest Cavaliers vs. Celtics odds from SportsLine consensus, while the over/under for total points scored is 233.5.

Before making any Cavaliers vs. Celtics picks, check out the NBA predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past six-plus seasons. The model enters Week 19 of the 2024-25 NBA season on a sizzling 147-106 roll on all top-rated NBA picks dating back to last season, returning nearly $4,000. It's also an outstanding 18-10 (64%) on top-rated spread picks this season. Anyone following at sportsbooks and on betting apps could have seen HUGE returns!

The model has simulated Cavaliers vs. Celtics 10,000 times and the results are in. We can tell you that the model is leaning Under on the point total, and it's also generated a point-spread pick that hits well over 50% of the time!

So who wins Cavaliers vs. Celtics, and  which side of the spread hits well over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NBA picks!