The Cleveland Cavaliers (40-26) attempt to avenge last week's defeat when they host the Boston Celtics (45-20) on Monday. After posting a pair of overtime victories over the Celtics early in the season, the Cavaliers suffered a 117-113 setback at Boston on Wednesday. The Celtics are coming off their third loss in four games, a 131-129 double-overtime home setback on Sunday against New York.

Tipoff at Rocket Mortgage FieldHouse is set for 7 p.m. ET. Cleveland is a 7.5-point favorite in the latest Cavaliers vs. Celtics odds from Caesars Sportsbook, while the over/under for total points scored is 218. (see up-to-date odds for every game this week on our NBA odds page). 

Before making any Celtics vs. Cavaliers picks, you NEED to check out the NBA predictions from the SportsLine Projection Model.

The model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past four-plus seasons. The model enters Week 21 of the 2022-23 NBA season a stunning 61-30 on all top-rated NBA picks this season, returning nearly $2,700. Anyone following it has seen HUGE returns!

The model knows Cleveland owns one of the best home records in the NBA at 27-7 and has won six of its last seven on its own court. The Cavaliers cruised to a 114-90 home victory against Detroit on Saturday. Darius Garland went 5-for-6 from 3-point range en route to 21 points, Donovan Mitchell scored 20 and Evan Mobley posted his 19th double-double with 12 points and 13 rebounds. However, Mitchell is questionable for Monday's matchup after spraining a finger on his left hand in the triumph.

The model also knows Boston has suffered three consecutive losses only twice this season, most recently from Jan. 23-26. All five starters scored in double figures on Sunday, with Jayson Tatum (game-high 40 points, 11 rebounds) and Al Horford (20, 14) recording double-doubles. It was the fifth in six contests for Tatum, who finished with 41 points, 11 boards and eight assists in the Celtics' home triumph over Cleveland last week.

Now, it has set its sights on Cavaliers vs. Celtics. We can tell you the model is leaning Over the total, and it also says one side of the spread hits in almost 60% of simulations! You ABSOLUTELY need to see it before locking in any NBA picks.

So who wins Cavaliers vs. Celtics? And which side of the spread hits in almost 60% of the simulations? ... Join SportsLine now to find out which side of the Celtics vs. Cavaliers spread you should be all over on Monday, all from the model that has crushed its top-rated NBA picks against the spread!