Teams trending in opposite directions meet in the series finale when the St. Louis Cardinals battle the Atlanta Braves on Wednesday afternoon. The Cardinals (10-14), who have lost five of six, are just 2-10 on the road this season. The Braves (9-14), who have won four of five, are 7-3 on their home field in 2025.

First pitch from Truist Park in Atlanta is set for 12:15 p.m. ET. The Cardinals have won seven of the last 10 meetings against the Braves. Atlanta is a -168 favorite on the money line (risk $168 to win $100) in the latest Cardinals vs. Braves odds, while the total number of runs Vegas thinks will be scored, or the over/under, is 9. 

Before making any Cardinals vs. Braves picks or MLB predictions, you need to see what the SportsLine Projection Model has to say.

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The model has simulated Cardinals vs. Braves 10,000 times and the results are in. We can tell you the model is leaning Under on the run total, and it also says one side of the money line is the better value!

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