The sixth-seeded BYU Cougars and third-seeded Wisconsin Badgers clash in an East Regional second-round matchup on Saturday. The Cougars (25-9), who have reached the second round for just the second time since 2012, are 16-34 overall in the tournament. The Badgers (27-9), who are 41-26 in the NCAA Tournament all-time, are making their 24th tournament appearance since 1999.

Tipoff from Ball Arena in Denver is set for 7:45 p.m. ET. Wisconsin is a 1.5-point favorite in the latest BYU vs. Wisconsin odds from SportsLine consensus, while the over/under for total points scored is 155.5. 

Before making any BYU vs. Wisconsin picks, check out the college basketball predictions from the SportsLine Projection Model.

The model simulates every Division 1 college basketball game 10,000 times. It enters the 2025 NCAA Tournament on a 228-166 roll (+2025) on all top-rated college basketball picks dating back to 2023. This model has also produced brackets that have beaten over 91% of CBS Sports entries in four of the last six tournaments and nailed 24 first-round upsets by double-digit seeds! Anyone following could have seen HUGE returns!

The model has simulated BYU vs. Wisconsin 10,000 times and the results are in. We can tell you that the model is leaning Under, and it also says one side of the spread cashes in 60% of simulations!

So who wins BYU vs. Wisconsin, and which side of the spread cashes in 60% simulations? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that is 228-166 (+2025) on top-rated college basketball pick and has nailed 24 double-digit upsets!