The No. 4 seed BYU Cougars will face the No. 5 seed Iowa State Cyclones in the Big 12 Tournament quarterfinals on Thursday afternoon. BYU finished the regular season on an eight-game winning streak, including a double-overtime win against Iowa State on March 4. The Cyclones were forced to play in the second round of the conference tournament after missing out on a top-four seed, but they were able to notch a 76-56 win over Cincinnati.   

Tipoff is set for 12:30 p.m. on Thursday at the T-Mobile Center in Kansas City. Iowa State is favored by 3.5 points in the latest BYU vs. Iowa State odds, while the over/under is 146.5 points, per SportsLine consensus. Before entering any Iowa State vs. BYU picks, you'll want to see the college basketball predictions from the model at SportsLine.

The model simulates every Division 1 college basketball game 10,000 times. It enters conference championship week on a 225-165 roll (+1873) on all top-rated college basketball picks dating back to 2023. Anyone following could have seen HUGE returns!

The model has simulated BYU vs. Iowa State 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in almost 60% of simulations. You can only see the pick at SportsLine.

So who wins BYU vs. Iowa State? And which side of the spread hits almost 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks.