The Butler Bulldogs (13-15) and the Villanova Wildcats (17-12) square off in a Big East contest on Saturday. On Wednesday, No. 7 St. John's knocked off Butler 76-70. The Wildcats have won two consecutive games. On Feb. 26, Villanova outlasted Seton Hall 59-54.

Tipoff is scheduled for noon ET at Finneran Pavilion in Villanova, Pa. The latest Butler vs. Villanova odds from SportsLine consensus list Villanova as a 6.5-point home favorite, while the over/under for total points scored is 145.5. 

Before entering any Butler vs. Villanova picks, you'll want to see the college basketball predictions from the model at SportsLine.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 17 of the 2024-25 season on a 220-160 roll (+2005) on all top-rated college basketball picks dating back to 2023. Anyone following could have seen HUGE returns!

The model has simulated Butler vs. Villanova 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread hits in 60% of simulations!

So who wins Butler vs. Villanova, and which side of the spread hits in 60% of simulations? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks!