Mid-American Conference teams trending in opposite directions clash when the Buffalo Bulls battle the Eastern Michigan Eagles in MACtion on Wednesday night. Buffalo is coming off a 51-48 overtime win over Ball State on Nov. 12, while Eastern Michigan dropped a 35-10 decision at Ohio last Wednesday. The Bulls (6-4, 4-2 MAC), who are tied for fourth in the conference, are 2-3 on the road in 2024. The Eagles (5-5, 2-4 MAC), who are tied for eighth in the MAC, are 3-2 on their home field.

Kickoff is set for 7 p.m. ET at Rynearson Stadium in Ypsilanti, Mich. The Bulls are 21-point favorites in the latest Buffalo vs. Eastern Michigan odds via SportsLine consensus, while the over/under for total points scored is 52.

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The model has simulated Buffalo vs. Eastern Michigan 10,000 times and the results are in. We can tell you that the model is leaning Over and it also says one side of the spread hits more than 50% of the time!

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