The Milwaukee Bucks battle the Philadelphia 76ers in an NBA season opener for both teams on Wednesday night. Milwaukee finished third in the Eastern Conference at 49-33 a year ago, while Philadelphia was the seventh seed at 47-35. Milwaukee small forward Khris Middleton is not expected to play as he continues to rehab a surgically repaired ankle.

Tipoff from Wells Fargo Center in Philadelphia is set for 7:30 p.m. ET. The SportsLine consensus lists Philadelphia as the 2.5-point favorite in the latest Bucks vs. 76ers odds, while the over/under for total points scored is 224.5 (see up-to-date odds for every game this week on our NBA odds page). 

Before you make any Bucks vs. 76ers picks, you NEED to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past five-plus seasons. The model ended the 2023-24 season on a sizzling 94-61 roll on all top-rated NBA picks, returning more than $2,800. Anyone following has seen HUGE returns!

The model knows 76ers center Joel Embiid (knee) is a difference-maker when healthy. Although listed as questionable, he is expected to play. Last season in 39 games, all starts, he averaged 34.7 points, 11 rebounds, 5.6 assists, 1.7 blocks and 1.2 steals. He connected on 52.9% of his field goals, including 38.8% from 3-point range, and 88.3% from the free throw line. Embiid has played in 433 career games, averaging 27.9 points, 11.2 rebounds and 3.6 assists.

The model also knows Milwaukee is led by power forward Giannis Antetokounmpo, who is a two-time MVP. In 73 starts last season, Antetokounmpo averaged 30.4 points, 11.5 rebounds, 6.5 assists, 1.2 steals and 1.1 blocks in 35.2 minutes. He connected on 61.1% of his field goals and 65.7% of his free throws. He has played well against the 76ers throughout his career, averaging 24.8 points, 11.6 rebounds and 5.5 assists vs. Philadelphia.

The model has simulated Bucks vs. 76ers 10,000 times and the results are in. We can tell you that the model is leaning Over on the point total, and it also says one side of the spread hits in well over 50% of simulations!

Who wins Bucks vs. 76ers, and which side of the spread hits in well over 50% of simulations? ... Join SportsLine right now to find out which side of the spread you should be all over, all from the model on a 94-61 roll on top-rated NBA picks!