Week 10 of the NFL season concludes with Monday Night Football between the Buffalo Bills and Denver Broncos at Highmark Stadium. Kickoff is scheduled for 8:15 p.m. ET. Buffalo is a 7.5-point favorite in the latest Bills vs. Broncos odds, while the over/under for total points scored is 47.5. Before you make any Broncos vs. Bills picks or NFL predictions, you need to see what the SportsLine Projection Model has to say.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 10 of the 2023 NFL season on an incredible 174-123 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 28-15 roll on top-rated NFL picks since Week 7 of last season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

The model knows that Stefon Diggs has been one of the best receivers in the league once again this season. The former All-Pro wideout leads the NFL in receptions (70). Entering the week, he also ranked second, behind only Tyreek Hill, in receiving touchdowns (seven) and third in receiving yards (834).

The model also has taken into account that Denver's defense has vastly improved over the last three weeks. Over the first five games of the season, the Broncos allowed 36.2 points and 450.6 yards per game and went 1-4. In the last three weeks, Denver has given up just 15.0 points and 331.7 yards per game. The Broncos are 2-1 over that stretch.

Now, the model has set its sights on Bills vs. Broncos. We can tell you the model is leaning Over the total, projecting 48 points, and it also says one side of the spread cashes in almost 60% of simulations! You ABSOLUTELY need to see it before locking in any NFL picks.

So who wins Broncos vs. Bills on Monday Night Football, and which side of the spread hits almost 60% of the time? Join SportsLine now to see which side of the Bills vs. Broncos spread to back, all from the model that's on an incredible 174-123 run!