Two of the most successful teams in UEFA Champions League history will meet in the 2024-25 Champions League Round of 16, with the first leg taking place on Wednesday on Paramount+. Spanish giants, Barcelona, will visit Portuguese club, Benfica, and these teams have combined for seven UCL championships across 15 Champions League Final appearances. Barca advanced directly to the Round of 16 via their performance in the league phase, while Benfica reached this 2024-25 UEFA Champions League round after defeating Monaco in the knockout phase playoffs. Stream the match live on Paramount+, which you can now try free for the first seven days when you sign up here.

Kickoff is at 3 p.m. ET from Estádio da Luz in Lisbon, Portugal. The latest Barcelona vs. Benfica odds list Barca as the -120 road favorites (risk $120 to win $100) on the 90-minute money line, with Benfica as the +280 underdogs (risk $100 to win $280). A draw is priced at +310, and the over/under for total goals is 3.5. Wednesday's match will be on Paramount+, which is free for the first week when you sign up here.

Paramount+ is the place to watch the Champions League this season. A subscription also gives you access to other sports content, including the UEFA Europa League, Serie A, EFL League One, NFL on CBS, Big Ten on CBS and countless movies and shows. You can now get a free 7-day trial, so sign up right here. 

Before you lock in your Barcelona vs. Benfica picks or make any UEFA Champions League predictions, you need to see what proven soccer expert Martin Green has to say.

After working in the sports betting industry for several years, Green became a professional sports writer and handicapper and has covered the game worldwide. Last year, he was profitable in multiple areas on his soccer picks, including Euro qualifying (+6.30 units), the EFL Cup (+4.47), the FA Cup (+3.07) and the Champions League (+3.05) among others.

Green has taken an in-depth look at the Barcelona vs. Benfica match and has locked in three CONFIDENT best bets while offering a full breakdown of this Champions League matchup! You ABSOLUTELY need to see his pick and analysis before making any selections of your own. Don't forget to stream the match on Paramount+.

So where does all the betting value lie for Barcelona vs. Benfica in the UEFA Champions League Round of 16? ... Join SportsLine now to see Martin Green's picks for Barcelona vs. Benfica, all from the insider who is tuned into leagues all over the world!