The No. 4 seed Arizona Wildcats will face the No. 5 seed Oregon Ducks in one of the most intriguing second-round games in the NCAA Tournament on Sunday night. Arizona crushed No. 13 seed Akron in the first round on Friday in a 93-65 final. Oregon was equally dominant in the first round, beating No. 12 seed Liberty by 29 points.  

Tip-off from Climate Pledge Arena in Seattle will be approximately 9:40 p.m. ET. The Wildcats are 4.5-point favorites in the latest Oregon vs. Arizona odds, via SportsLine consensus, while the over/under for total points is 151.5, down three from the opening line. The Wildcats are -188 money-line favorites.  

Before making any Oregon vs. Arizona picks, check out the college basketball predictions from the SportsLine Projection Model.

The model simulates every Division 1 college basketball game 10,000 times. It entered the 2025 NCAA Tournament on a 228-166 roll (+2025) on all top-rated college basketball picks dating back to 2023. This model has also produced brackets that have beaten over 91% of CBS Sports entries in four of the last six tournaments and nailed 24 first-round upsets by double-digit seeds! Anyone following could have seen HUGE returns!

The model has simulated Oregon vs. Arizona 10,000 times and the results are in. We can tell you that the model is leaning Under, and it also says one side of the spread hits in well over 50% of simulations!

So who wins Oregon vs. Arizona, and which side of the spread hits in well over 50% of simulations? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that is 228-166 (+2025) on top-rated college basketball pick and has nailed 24 double-digit upsets!