The Arizona Wildcats look to snap a five game losing streak as they host Big 12 rivals, the Houston Cougars on Friday night. Arizona (3-6) enters off a bye week following a 56-12 drubbing at Central Florida in Week 10. Houston (4-5) has won two straight games, most recently a 24-19 victory over No. 17 Kansas State, 24-19. The Wildcats are 1-3 lifetime vs. the Cougars, including losses in 2017 and 2018. Houston is 5-4 against the spread, while Arizona is 1-8 ATS in 2024.

Kickoff from Arizona Stadium is scheduled for 10:15 p.m. ET. The Wildcats are 1.5-point favorites in the latest Arizona vs. Houston odds from SportsLine consensus, while the over/under for total points scored is 45.5, up three points from the opener. Arizona is the -117 money line favorite (risk $117 to win $100), while Houston is the -104 underdog. Before making any Houston vs. Arizona picks or CFB predictions, you need to see what the SportsLine Projection Model has to say.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of well over $2,000 for $100 players on its top-rated college spread football picks, and it is a strong 18-12 on all top-rated picks over the past seven weeks of this season. Anyone following has seen STRONG returns!

The model has simulated Arizona vs. Houston 10,000 times and the results are in. We can tell you the model is leaning Over on the total, and it also says one side of the spread hits nearly 70% of the time!

Who wins Wildcats vs. Cougars, and which side of the spread hits well nearly 70% of the time? Join SportsLine right now to find out which side of the spread you should be all over, all from the model who is a strong 18-12 on all top-rated picks over the past seven weeks!