The No. 2 Duke Blue Devils host the No. 12 Arizona Wildcats in a high-profile, non-conference matchup at 7 p.m. ET on Friday. For this game, SportsLine consensus lists Duke as a 5.5-point favorite, while the over/under is set at 154.5 (see up-to-date odds for every game this week on our college basketball odds page). 

Before making any Arizona vs. Duke picks, you NEED to check out the college basketball predictions from the SportsLine Projection Model.

The model simulates every Division I college basketball game 10,000 times. It went 85-55 on all top-rated college basketball picks last season, returning more than $1,600 for $100 players. Anyone who followed it saw HUGE returns!

The model knows Arizona was utterly dominant in its season opener. The Wildcats scored more points per possession (1.57) than any team in the country in their debut, and Arizona had eight players score in double figures. Arizona also posted a top-15 mark nationally in offensive efficiency last season and finished No. 2 in the country with 18.9 assists per game.

The model also knows Duke is coming off a tremendous defensive season and a strong season opener of its own. The Blue Devils allowed fewer than 0.97 points per possession last season, and Duke gave up only 34% shooting and 22% from 3-point range in the season opener. Duke also finished in the top 15 nationally in opponent shooting efficiency in 2022-23, and the Blue Devils blocked more than 12% of opponent shot attempts.

Now, it has set its sights on Arizona vs. Duke. We can tell you the model is leaning Under the total, and it also says one side of the spread hits in more than 50% of simulations! You ABSOLUTELY need to see it before locking in any college basketball picks.

Who wins Arizona vs. Duke? And which side of the spread hits in more than 50% of simulations? ... Join SportsLine right now to find out which side of the Arizona vs. Duke spread you should be all over Friday, all from the model on an 85-55 roll on top-rated college basketball picks!