We've got another exciting Eastern Conference matchup on Wednesday's NBA schedule as the Detroit Pistons will visit the Philadelphia 76ers. Philadelphia is 1-2 overall and 0-1 at home, while Detroit is 0-4 overall and 0-2 on the road. The Sixers have won eight straight meetings with the Pistons.

Tipoff is at 7 p.m. ET at Wells Fargo Center in Philadelphia. The Sixers are favored by 3.5 points in the latest 76ers vs. Pistons odds, per SportsLine consensus, and the over/under is 218.5 points (see up-to-date odds for every game this week on our NBA odds page). 

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The model has simulated Sixers vs. Pistons 10,000 times and the results are in. We can tell you that the model is leaning Over on the point total, and it also says one side of the spread hits in nearly 60% of simulations!

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