The Philadelphia 76ers will return from an extended break when they host the Indiana Pacers on Friday night. Philadelphia has won three of its first four games in December, and it has not played since beating Chicago by eight points on Sunday. Indiana has dropped five of its last six games, including a 113-109 setback against Charlotte on Sunday.  

Tipoff is set for 7 p.m. ET on Friday at Wells Fargo Center. The 76ers are favored by 6.5 points in the latest 76ers vs. Pacers odds, while the over/under is 227 points, per SportsLine consensus. Before entering any Pacers vs. 76ers picks, you'll want to see the NBA predictions from the model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past six-plus seasons. The model enters Week 8 of the 2024-25 NBA season on a sizzling 121-83 roll on all top-rated NBA picks dating back to last season, returning more than $3,000. Anyone following at sportsbooks and on betting apps has seen huge returns.

The model has simulated 76ers vs. Pacers 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 50% of simulations. You can only see the pick at SportsLine.

So who wins 76ers vs. Pacers? And which side of the spread hits well over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NBA picks.